Mutagenesis and morphological transformation of mammalian cells by a non-bay-region polycyclic cyclopenta(cd)pyrene and its 3,4-oxide.
نویسندگان
چکیده
Cyclopenta(cd)pyrene, a constituent of environmental emissions, has been found to mutate and transform mammalian cells in culture. Cyclopenta(cd)pyrene 3,4-oxide, a presumed metabolite, was found to be a direct-acting mutagen and to transform mammalian cells. These results suggest that cyclopenta(cd)pyrene 3,4-oxide may be an ultimate mutagenic form of the parent hydrocarbon.
منابع مشابه
Mutagenesis and Morphological Transformation of Mammalian Cells by a Non-Bay-Region Polycyclic Cyclopenta( cd)py rene and Its 3,4-Oxide1
Cyclopenta(ccOpyrene, a constituent of environmental emis sions, has been found to mutate and transform mammalian cells in culture. Cyclopenta(cd)pyrene 3,4-oxide, a presumed metabolite, was found to be a direct-acting mutagen and to transform mammalian cells. These results suggest that cyclopenta(cd)pyrene 3,4-oxide may be an ultimate mutagenic form of the parent hydrocarbon. INTRODUCTION The ...
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ورودعنوان ژورنال:
- Cancer research
دوره 40 12 شماره
صفحات -
تاریخ انتشار 1980